We all know that there’s a drug war against marijuana still raging in many countries around the world. So, we can easily say that the question of how long-term marijuana use effects the human brain is a pivotal question in its legalization. The real and ugly truth is that the alcohol (still) remains legal despite lot of evidence to the dangers of long-term use. So, the fight to make marijuana available both with regard to its medical properties and non-medical uses has frequently hinged on the various claims made about marijuana’s effects on the recreational user.
And, fortunately, the debate can finally move out from the realm of opinion into scientific evidence. And now you probably ask yourself – how? Well, a group of researchers from the University of Texas just published their research into the long-term effects of marijuana use on the brain in PNAS (Proceedings of the National Academy of Sciences).
Here’s what you need to know – the researcher helped dispel the dying myth that marijuana use lowers IQ, and actually provides more evidence to marijuana’s potential role in fighting Alzheimer’s.
You should know that this study revealed that earlier onset of regular marijuana use leads to greater structural and functional connectivity in the brain. The most significant increases in connectivity appear as an individual begins using marijuana, with results showing that the severity of use is directly correlated to greater connectivity.
Yes, the results from this study need to be confirmed with a larger sample (this was based on roughly 100 participants). But still, the preliminary results seemed promising. More research needed to be done in order to see if these differences are caused by, or simply associated with, long term marijuana use. The UT study also foundreduced gray matter in the OFC (orbitofrontalcortex) in long-term users (which is a brain region associated with addiction). It was unclear whether this region is simply smaller in regular users (explaining their regular use) or if the use actually contributed to structural brain changes.
Another, more recent study, published in the Journal of Neuroscience, also with 100 people (50 adolescents and 50 adults) found no significant differences in brain structure relating to daily or non-daily cannabis consumption. Which pokes holes in the interpretation that cannabis consumption was the driver in the gray matter differences seen in University of Texas study.
Many experts say that these results will also need to be viewed in light of other researcher showing that cannabinoids actually promote brain cell growth/regrowth (neurogenesis) even in adults. Why this could possibly remain illegal anywhere, is an important question, and hopefully people will continue to inform themselves and others on the topic. We really hope you enjoyed this article and don’t forget to share it with your friends and family. Thank You.